A prospective, randomized, double-blind comparison of bilateral and right unilateral electroconvulsive therapy at different stimulus intensities.

@article{Sackeim2000APR,
  title={A prospective, randomized, double-blind comparison of bilateral and right unilateral electroconvulsive therapy at different stimulus intensities.},
  author={Harold A. Sackeim and Joan Prudic and D. P. Devanand and M. Nobler and Sarah H. Lisanby and Shoshana Peyser and Linda Fitzsimons and Brian Moody and Jeffrey Clark},
  journal={Archives of general psychiatry},
  year={2000},
  volume={57 5},
  pages={425-34}
}
BACKGROUND Controversy persists about the use of right unilateral (RUL) and bilateral (BL) electroconvulsive therapy (ECT). While RUL ECT results in less severe short-term and long-term cognitive effects, there is concern that it is less efficacious than BL ECT. METHODS In a double-blind study, 80 depressed patients were randomized to RULECT, with electrical dosages 50%, 150%, or 500% above the seizure threshold, or BL ECT, with an electrical dosage 150% above the threshold. Depression… CONTINUE READING
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