A proposed autacoid mechanism controlling mastocyte behaviour

@article{Aloe2005APA,
  title={A proposed autacoid mechanism controlling mastocyte behaviour},
  author={L. Aloe and A. Leon and R. Levi-Montalcini},
  journal={Agents and Actions},
  year={2005},
  volume={39},
  pages={C145-C147}
}
Evidence is provided here supporting the existence of a novel autacoid mechanism negatively modulating mast cell behaviour in response to noxious stimuliin vivo; hence, the denomination “autacoid local inflammation antagonism” (ALIA). In particular, as lipid amides of theN-acylethanolamine type have been reported to accumulate in tissues in degenerative inflammatory conditions, we examined whether theseN-acylated lipids could exert regulatory effects on mast cell activationin vivo. The results… Expand
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139 Citations
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139 Citations

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