A proposed autacoid mechanism controlling mastocyte behaviour
@article{Aloe2005APA, title={A proposed autacoid mechanism controlling mastocyte behaviour}, author={L. Aloe and A. Leon and R. Levi-Montalcini}, journal={Agents and Actions}, year={2005}, volume={39}, pages={C145-C147} }
Evidence is provided here supporting the existence of a novel autacoid mechanism negatively modulating mast cell behaviour in response to noxious stimuliin vivo; hence, the denomination “autacoid local inflammation antagonism” (ALIA). In particular, as lipid amides of theN-acylethanolamine type have been reported to accumulate in tissues in degenerative inflammatory conditions, we examined whether theseN-acylated lipids could exert regulatory effects on mast cell activationin vivo. The results… Expand
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