A proline-rich polypeptide from ovine colostrum: colostrinin with immunomodulatory activity.

  • Michał Zimecki
  • Published 2008 in Advances in experimental medicine and biology


A proline-rich polypeptide (PRP), later called colostrinin (CLN), was originally found as a fraction accompanying sheep colostral immunoglobulins. Extensive in vitro and in vivo studies in mice revealed its interesting T cell-tropic activities. The polypeptide promoted T cell maturation from early thymic precursors that acquired the phenotype and function… (More)
DOI: 10.1007/978-0-387-74087-4_9


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