A programmable microvalve-based microfluidic array for characterization of neurotoxin-induced responses of individual C. elegans.

@article{Ma2009APM,
  title={A programmable microvalve-based microfluidic array for characterization of neurotoxin-induced responses of individual C. elegans.},
  author={Hui Ma and Lei Jiang and Weiwei Shi and Jianhua Qin and Bingcheng Lin},
  journal={Biomicrofluidics},
  year={2009},
  volume={3 4},
  pages={44114}
}
The soil dwelling nematode Caenorhabditis elegans (C. elegans) is an excellent model organism for the study of numerous disease including neurodegenerative disease. In this study, a programmable microvalve-based microfluidic array for real-time and long-term monitoring of the neurotoxin-induced responses of the individual C. elegans was developed. The device consisted of a flow layer and a control layer, which were used for worm manipulation. By activating the programmable microvalves in the… CONTINUE READING
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