• DOI:10.1016/0010-468X(79)90025-4
Corpus ID: 38435927

A program package for simulation and parameter estimation in pharmacokinetic systems.

@article{DArgenio1979APP,
  title={A program package for simulation and parameter estimation in pharmacokinetic systems.},
  author={D. Z. D'Argenio and A. Schumitzky},
  journal={Computer programs in biomedicine},
  year={1979},
  volume={9 2},
  pages={
          115-34
        }
}

D. Z. D'Argenio, A. Schumitzky

Published 1979

Computer Science, Medicine

Computer programs in biomedicine

A set of programs is presented which has been developed for parameter estimation and simulation of models arising from pharmacokinetic applications. The programs can accommodate linear and nonlinear models with multiple inputs and multiple outputs. When the model is defined by differential equations, non-uniform repetitive dosage regimens can be handled. The model may also be entered in integrated form when single dose studies or uniform multiple dose studies are being considered. The programs… CONTINUE READING

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