A production of amino acids under possible primitive earth conditions.

@article{Miller1953APO,
  title={A production of amino acids under possible primitive earth conditions.},
  author={S. L. Miller},
  journal={Science},
  year={1953},
  volume={117 3046},
  pages={
          528-9
        }
}
atmosphere of methane, ammonia, water, and hydrogen instead of carbon dioxide, nitrogen, oxygen, and water was suggested by Oparin (1) and has been-given emphasis recently by Urey (2) and Bernal (3). In order to test this hypothesis, an apparatus was built to circulate CHI4, NH3, H2O, and H2 past an electric discharge. The resulting mixture has been tested for amino acids by paper chromatography. Electrical discharge was used to form free radicals instead of ultraviolet light, because quartz… 

Amino Acid Synthesis in a Supercritical Carbon Dioxide - Water System

Using a supercritical CO2/liquid H2O (10:1) system which mimicked crust soda fountains, production of amino acids from hydroxylamine and keto acids is demonstrated, lighting up a new pathway in the study of life’s origin.

Abiotic synthesis of amino acids and imidazole by proton irradiation of simulated primitive earth atmospheres

Proton irradiation of simulated primitive earth atmosphere was performed, and amino acids and imidazole were analyzed. A mixture of carbon monoxide and nitrogen over water was irradiated by high

Amino acid synthesis by glow discharge electrolysis - A possible route for prebiotic synthesis of amino acids

Accumulated results indicate that the formation of amino acids occurs rather easily, in many ways, under various inferred prebiotic conditions.

Amino acids derivatives synthesis from nitrogen, carbon and water by electric discharges

Electric discharges between a pair of carbon electrodes were continued for 50 days in a vessel which initially contained nitrogen at a pressure of 15 cm Hg and 200 ml of water and indicated the presence of hydantoic acid, N-formylglycine, diketopiperazine, and polymers of glycine.

Abiotic synthesis of amino acids by x-ray irradiation of simple inorganic gases

1–2 keV x-ray irradiation was carried out using a synchrotron radiation source on simulated primitive earth environment: a gas mixture of carbon monoxide, nitrogen, and water at atmospheric pressure.

Amino Acid Formation in Gas Mixtures by High Energy Particle Irradiation

It is suggested that cosmic rays were one of the most important energy sources for the synthesis of amino acids on the primitive earth.

The atmosphere of the primitive Earth and the prebiotic synthesis of amino acids

The ratios of amino acids in the meteorite show a close correspondence to the ratios from the electric discharge synthesis, indicating that the amino acids on the parent body of the carbonaceous chondrites were synthesized by electric discharges or by an analogous process.

Photochemical Synthesis of Ammonia and Amino Acids from Nitrous Oxide.

Abiotic synthesis of ammonia (NH3) and amino acids is important for the origin of life and early evolution. Ammonia and organic nitrogen species may be produced from nitrous oxide (N2O), which is a

FORMATION OF THE BUILDING BLOCKS OF PRIMITIVE LIFE

Life defined as a chemical system capable of transferring its molecular information via self-reproduction and of evolving probably originated from the reaction of reduced carbon-based organic matter
...

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His cytological reflections on chromosomes as the physical basis of heredity, and on the Golgi bodies and mitochondria, illuminate the subject, while his all-too-brief discussion of certain facts of experimental embryology runs along a somewhat unfamiliar track.

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    Proceedings of the National Academy of Sciences of the United States of America
  • 1952
This work was done under contract N7-onr 434 Task Order III, Naval Department, Office of Naval Research, and made use of a homotopy lemma similar to Spanier's lemma.

Yale Univ

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