A procedure for tissue freezing and processing applicable to both intra-operative frozen section diagnosis and tissue banking in surgical pathology

@article{Steu2008APF,
  title={A procedure for tissue freezing and processing applicable to both intra-operative frozen section diagnosis and tissue banking in surgical pathology},
  author={Susanne Steu and Maya Baucamp and Gabriela von Dach and Marion Bawohl and Susanne Dettwiler and Martina Storz and Holger Moch and Peter Schraml},
  journal={Virchows Archiv},
  year={2008},
  volume={452},
  pages={305-312}
}
Different methods for snap freezing surgical human tissue specimens exist. At pathology institutes with higher work loads, solid carbon dioxide, freezing sprays, and cryostat freezing are commonly used as coolants for diagnosing frozen tissue sections, whereas for tissue banking, liquid nitrogen or isopentane cooled with liquid nitrogen is preferred. Freezing tissues for diagnostic and research purposes are therefore often time consuming, laborious, even hazardous, and not user friendly. In… CONTINUE READING

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