A probe for a histaminergic component of drinking in the rat.

@article{Kraly1983APF,
  title={A probe for a histaminergic component of drinking in the rat.},
  author={F. Scott Kraly},
  journal={Physiology & behavior},
  year={1983},
  volume={31 2},
  pages={229-32}
}
Systemic antagonism of H1 or H2 receptors for histamine attenuated drinking elicited by SC 20 mg/kg histamine in adult male Sprague-Dawley rats. The H1 antagonist dexbrompheniramine (DXB; 0.5-16 mg/kg) and the H2 antagonist cimetidine (C; 0.5-100 mg/kg) each inhibited drinking elicited by histamine when given IP 10 min prior to SC histamine: The lowest doses to produce a statistically significant inhibition of drinking were 2 mg/kg DXB and 32 mg/kg C. While 1 mg/kg DXB alone or 16 mg/kg DXB… CONTINUE READING

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