A probable dual mode of action for both L- and D-lactate neuroprotection in cerebral ischemia.

Abstract

Lactate has been shown to offer neuroprotection in several pathologic conditions. This beneficial effect has been attributed to its use as an alternative energy substrate. However, recent description of the expression of the HCA1 receptor for lactate in the central nervous system calls for reassessment of the mechanism by which lactate exerts its… (More)
DOI: 10.1038/jcbfm.2015.115

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Cite this paper

@article{Castillo2015APD, title={A probable dual mode of action for both L- and D-lactate neuroprotection in cerebral ischemia.}, author={Ximena Castillo and Katia Rosafio and Matthias T. Wyss and Konstantin Drandarov and Alfred Buck and Luc Pellerin and Bruno Weber and Lorenz Hirt}, journal={Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism}, year={2015}, volume={35 10}, pages={1561-9} }