A primate-specific acceleration in the evolution of the caspase-dependent apoptosis pathway.

Abstract

Programmed cell death, or apoptosis, plays an essential role in mammalian development, especially the development of the nervous system. Here, we systematically examine the molecular evolution of the mammalian intrinsic apoptosis program. We divided the program into its several constituent pathways and examined the evolution of each pathway in diverse… (More)

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@article{Vallender2006APA, title={A primate-specific acceleration in the evolution of the caspase-dependent apoptosis pathway.}, author={Eric J. Vallender and Bruce T. Lahn}, journal={Human molecular genetics}, year={2006}, volume={15 20}, pages={3034-40} }