A primary tumor promotes dormancy of solitary tumor cells before inhibiting angiogenesis.

@article{Guba2001APT,
  title={A primary tumor promotes dormancy of solitary tumor cells before inhibiting angiogenesis.},
  author={Markus Guba and Grigore Cernaianu and Gudrun Koehl and Edward Kenneth Geissler and K. W. Jauch and Matthias Anthuber and Werner Falk and Markus Steinbauer},
  journal={Cancer research},
  year={2001},
  volume={61 14},
  pages={5575-9}
}
Mechanisms that regulate the transition of micrometastases from clinically undetectable and dormant to progressively growing are critically important but poorly understood in cancer biology. Here we examined the effect of a primary tumor on the growth of solitary tumor cells in the mouse liver, as well as on the development of tumor angiogenesis in a dorsal skin-fold chamber. s.c. placement of a CT-26 (BALB/c-derived mouse colon carcinoma) primary tumor markedly inhibited development of liver… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 64 extracted citations

Cell density sensing and size determination.

Development, growth & differentiation • 2011
View 4 Excerpts
Highly Influenced

Hypocrisy and Corruption: How Disparities in Power Shape the Evolution of Social Control.

Evolutionary psychology : an international journal of evolutionary approaches to psychology and behavior • 2018
View 1 Excerpt

Using Ordinary Differential Equations to Explore Cancer-Immune Dynamics and Tumor Dormancy

- KathleenP.Wilkie, - PhilipHahnfeldt, - LynnHlatky
2016
View 1 Excerpt

References

Publications referenced by this paper.
Showing 1-10 of 24 references

Immune response to green fluorescent protein: implications for gene therapy

R. Stripecke, V. M. Carmen, +3 authors D. Kohn
Gene Ther.,6: • 1999
View 1 Excerpt

Similar Papers

Loading similar papers…