A preliminary study of the dental implant therapy--initial osteogenesis of human mesenchymal stem (HMS0014) cells on titanium discs with different surface modifications.

Abstract

HMS0014 cells were GBR-engineered to proliferate and differentiate into mature osteoblast(Ob)-like cells, which initiated hard tissue matrix deposition in both monolayer and PuraMatrix 3-D cultures. Subsequently, the osteogenesis initiated with attachment/adhesion of HMS0014 cells on either Titanium (Ti) or Ti alloy discs modified with osteoconductive… (More)

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