A preliminary evaluation of comparative effectiveness of riluzole in therapeutic regimen for irritable bowel syndrome.

@article{Mishra2014APE,
  title={A preliminary evaluation of comparative effectiveness of riluzole in therapeutic regimen for irritable bowel syndrome.},
  author={Surya Prakash Mishra and Sunit Kumar Shukla and Bajrang Lal Pandey},
  journal={Asian Pacific journal of tropical biomedicine},
  year={2014},
  volume={4 Suppl 1},
  pages={S335-40}
}
OBJECTIVE To develop agents that are specifically effective in controlling the key disturbance of visceral hyperalgesia besides abating of associated multiple symptoms, and evaluate comparative effectiveness for IBS symptom relief for standard regimen (antispasmodic and probiotic) and add-on amitriptyine or riluzole regimens following two weeks administration. METHODS 108 patients with visceral hypersensitivity accompanying IBS, divided into three groups were studied. First group received… CONTINUE READING
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