A preliminary controlled study to determine whether whole-plant cannabis extracts can improve intractable neurogenic symptoms

  title={A preliminary controlled study to determine whether whole-plant cannabis extracts can improve intractable neurogenic symptoms},
  author={Derick T. Wade and Philip J. Robson and Heather House and Petra Makela and Julia Aram},
  journal={Clinical Rehabilitation},
  pages={21 - 29}
Objectives: To determine whether plant-derived cannabis medicinal extracts (CME) can alleviate neurogenic symptoms unresponsive to standard treatment, and to quantify adverse effects. Design: A consecutive series of double-blind, randomized, placebo-controlled single-patient cross-over trials with two-week treatment periods. Setting: Patients attended as outpatients, but took the CME at home. Subjects: Twenty-four patients with multiple sclerosis (18), spinal cord injury (4), brachial plexus… 

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