A practical overview of tizanidine use for spasticity secondary to multiple sclerosis, stroke, and spinal cord injury

@article{Kamen2008APO,
  title={A practical overview of tizanidine use for spasticity secondary to multiple sclerosis, stroke, and spinal cord injury},
  author={Leonard B. Kamen and H. Henney and J. D. Runyan},
  journal={Current Medical Research and Opinion},
  year={2008},
  volume={24},
  pages={425 - 439}
}
ABSTRACT Objective: Tizanidine is an imidazoline central α2-adrenoceptor agonist widely used to manage spasticity secondary to conditions such as multiple sclerosis (MS), stroke, and spinal cord injury (SCI). While there is widespread use of tizanidine in clinical practice, little practical information is available to assist prescribers with the effective use of tizanidine for spasticity management. The aim of this review is to provide an up-to-date overview of tizanidine and its use in the… Expand
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