A potentially crucial role of the PKD1 C-terminal tail in renal prognosis

@inproceedings{Higashihara2017APC,
  title={A potentially crucial role of the PKD1 C-terminal tail in renal prognosis},
  author={Eiji Higashihara and Shigeo Horie and Moritoshi Kinoshita and Peter C. Harris and Takatsugu Okegawa and Mitsuhiro Tanbo and Hidehiko Hara and Tsuyoshi Yamaguchi and Kaori Shigemori and Haruna Kawano and Isao Miyazaki and Shinya Kaname and Kikuo Nutahara},
  booktitle={Clinical and Experimental Nephrology},
  year={2017}
}
Autosomal dominant polycystic disease (ADPKD) often results in renal failure. Recently, allelic influences of PKD1 mutation types on renal survival were extensively investigated. Here, we analyzed integrated influences of PKD1 mutation types and positions on renal survival. We included 338 (82 pedigrees) and 72 (12 pedigrees) patients with PKD1 and PKD2… CONTINUE READING