A potentially critical role of phospholipases in central nervous system ischemic, traumatic, and neurodegenerative disorders

@article{Phillis2004APC,
  title={A potentially critical role of phospholipases in central nervous system ischemic, traumatic, and neurodegenerative disorders},
  author={John W. Phillis and Michael H. O'Regan},
  journal={Brain Research Reviews},
  year={2004},
  volume={44},
  pages={13-47}
}
Phospholipases are a diverse group of enzymes whose activation may be responsible for the development of injury following insult to the brain. Amongst the numerous isoforms of phospholipase proteins expressed in mammals are 19 different phospholipase A2's (PLA2s), classified functionally as either secretory, calcium dependent, or calcium independent, 11 isozymes belonging to three structural groups of PLC, and 3 PLD gene products. Many of these phospholipases have been identified in selected… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 49 extracted citations

Similar Papers

Loading similar papers…