A potential role for immunotherapy in thyroid cancer by enhancing NY-ESO-1 cancer antigen expression.

@article{Gunda2014APR,
  title={A potential role for immunotherapy in thyroid cancer by enhancing NY-ESO-1 cancer antigen expression.},
  author={Viswanath Gunda and Dennie Tompers Frederick and M Jordana Bernasconi and Jennifer A Wargo and Sareh Parangi},
  journal={Thyroid : official journal of the American Thyroid Association},
  year={2014},
  volume={24 8},
  pages={1241-50}
}
BACKGROUND NY-ESO-1 is one of the most immunogenic members of the cancer/testis antigen family and its levels can be increased after exposure to demethylating and deacetylating agents. This cytoplasmic antigen can serve as a potent target for cancer immunotherapy and yet has not been well studied in differentiated thyroid cancer cells. METHODS We studied… CONTINUE READING