A potential role for hypothalamomedullary POMC projections in leptin-induced suppression of food intake.

@article{Zheng2010APR,
  title={A potential role for hypothalamomedullary POMC projections in leptin-induced suppression of food intake.},
  author={Huiyuan Zheng and Laurel M. Patterson and Christopher J Rhodes and Gwendolyn W. Louis and Karolina P Skibicka and Harvey J. Grill and Martin G Myers and H. -R. Berthoud},
  journal={American journal of physiology. Regulatory, integrative and comparative physiology},
  year={2010},
  volume={298 3},
  pages={R720-8}
}
Melanocortin-3/4 receptor ligands administered to the caudal brain stem potently modulate food intake by changing meal size. The origin of the endogenous ligands is unclear, because the arcuate nucleus of the hypothalamus and the nucleus of the solitary tract (NTS) harbor populations of proopiomelanocortin (POMC)-expressing neurons. Here we demonstrate that activation of hypothalamic POMC neurons leads to suppression of food intake and that this suppression is prevented by administration of a… CONTINUE READING
40 Citations
38 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 40 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 38 references

The Rat Brain in Stereotaxic Coordinates

  • G Paxinos, C. Watson
  • San Diego, CA: Academic,
  • 1986
Highly Influential
6 Excerpts

Similar Papers

Loading similar papers…