A potential role for hydrocortisone in the positive regulation of IL-15-activated NK-cell proliferation and survival.

@article{Perez2005APR,
  title={A potential role for hydrocortisone in the positive regulation of IL-15-activated NK-cell proliferation and survival.},
  author={Sonia Cristina Gualtieri de Andrade Perez and Louisa G. Mahaira and Fillio J Demirtzoglou and Panagiota A. Sotiropoulou and Panayotis Ioannidis and Eleni G. Iliopoulou and Angelos D. Gritzapis and Nectaria N. Sotiriadou and Constantin N. Baxevanis and Michael Papamichail},
  journal={Blood},
  year={2005},
  volume={106 1},
  pages={158-66}
}
Although glucocorticoids (GCs) have been described as acting mainly as anti-inflammatory and immunosuppressive drugs, they may also positively influence the immune system. In the present study, we demonstrate for the first time that hydrocortisone (HC), in synergy with interleukin-15 (IL-15), induces a dramatic increase in the expansion of peripheral blood-derived CD56+ cells, favoring the preferential outgrowth of classical natural killer (CD56+CD3- NK) over CD56+CD3+ natural killer T (NKT… CONTINUE READING
15 Citations
63 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 15 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 63 references

Similar Papers

Loading similar papers…