A potential blood substitute from carboxylic dextran and oxyhemoglobin. III. Evaluations by perfusion of normal and ischemic guinea-pig heart.


Hemodynamic parameters of six groups of guinea-pig hearts were studied by the working heart technic of Neely. Three groups were respectively perfused with: Krebs-Henseleit, purified native hemoglobin 1gm/dl and hemoglobin conjugated to dextran benzene tetracarboxylate 1 gm/dl. Three other groups were perfused under the same conditions except that after 30… (More)


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