A potassium channel in the apical membrane of rabbit thick ascending limb of Henle's loop.

@article{Wang1990APC,
  title={A potassium channel in the apical membrane of rabbit thick ascending limb of Henle's loop.},
  author={Wen Feng. Wang and Stanley H. White and John J. Geibel and Gerhard Giebisch},
  journal={The American journal of physiology},
  year={1990},
  volume={258 2 Pt 2},
  pages={
          F244-53
        }
}
We used the patch-clamp technique to study the activity of single potassium channels in the apical membrane of isolated thick ascending limbs of Henle's loop (TAL) of rabbit kidneys. In cell-attached patches with NaCl Ringer or high-K+ solution in the bath and 140 mM K+ in the pipette, an inwardly rectifying K+ channel was observed with an inward slope conductance of 22.0 +/- 0.5 pS and outward slope conductance of 10.2 +/- 0.3 pS at 22 degrees C (n = 15). The channel was highly selective for K… CONTINUE READING
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