A postinfluenza model of Staphylococcus aureus pneumonia.

@article{Lee2010APM,
  title={A postinfluenza model of Staphylococcus aureus pneumonia.},
  author={Mei-ho Lee and Carlos Arrecubieta and Francis J. Martin and Alice Prince and Alain C. Borczuk and Franklin D. Lowy},
  journal={The Journal of infectious diseases},
  year={2010},
  volume={201 4},
  pages={
          508-15
        }
}
BACKGROUND Postinfluenza Staphylococcus aureus pneumonias are increasingly recognized as a major form of life-threatening infections. METHODS A mouse model of postinfluenza S. aureus pneumonia was developed. Mice were intranasally infected with bacteria alone or bacteria plus virus. Infection was assessed by mouse survival, lung histopathology, bacterial density in the lungs, and cellular response to infection. RESULTS Mice infected with both influenza virus and S. aureus showed higher… CONTINUE READING

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