A possible role of cholesterol-sphingomyelin/phosphatidylcholine in nuclear matrix during rat liver regeneration.

@article{Albi2003APR,
  title={A possible role of cholesterol-sphingomyelin/phosphatidylcholine in nuclear matrix during rat liver regeneration.},
  author={Elisabetta Albi and Samuela Cataldi and Graziella Rossi and Mariapia Viola Magni},
  journal={Journal of hepatology},
  year={2003},
  volume={38 5},
  pages={623-8}
}
BACKGROUND/AIMS Phospholipids and cholesterol in chromatin have been previously demonstrated. The lipid fraction changes during cell proliferation in relation to activation of enzymes of phospholipid metabolism. The aim of the present work is to clarify if chromatin lipids may derive or not from nuclear matrix and if they have different roles. METHODS The subnuclear fractions were isolated from rat hepatocyte nuclei and the lipid fraction was extracted and analysed by chromatography in normal… CONTINUE READING
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