A possible role of gonad and renal prostaglandin E2 on the development of hypertension in spontaneously hypertensive rats.

Abstract

A possible role of prostaglandin E2 (PGE2) in the regulation of blood pressure in spontaneously hypertensive rats (SHR) was investigated. The inhibition of PG synthesis by chronic indomethacin treatment accelerated the elevation of blood pressure with the tendency to decrease renal PGE2. We, therefore, confirmed that PGE2 in SHR may play a role in the… (More)

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@article{Matsudaira1985APR, title={A possible role of gonad and renal prostaglandin E2 on the development of hypertension in spontaneously hypertensive rats.}, author={Tatsuyuki Matsudaira and Hiroyuki Kogo and T. Satoh}, journal={Japanese journal of pharmacology}, year={1985}, volume={37 1}, pages={51-7} }