A possible role of chitin in the pathogenesis of asthma and allergy.

  title={A possible role of chitin in the pathogenesis of asthma and allergy.},
  author={Bendik Christian Brinchmann and Michael Bayat and Torbj\orn Br\ogger and Danson Vasanthan Muttuvelu and Anders Tj\onneland and Torben Sigsgaard},
  journal={Annals of agricultural and environmental medicine : AAEM},
  volume={18 1},
Chitin is the second most abundant polysaccharide in the world; it is found in insects, parasites and fungi. Chitinases break down chitin, and are a part of the defence mechanism against chitin-containing parasites in lower life forms. This review is based on the results of PubMed-searches using the search-terms: chitin, chitinase, allergy and asthma. Research in murine models has proved that chitin is a size-dependent microbial-associated molecular pattern, with the ability to induce an… CONTINUE READING
10 Citations
44 References
Similar Papers


Publications citing this paper.
Showing 1-10 of 10 extracted citations


Publications referenced by this paper.
Showing 1-10 of 44 references

The role of innate immunity in occupational allergy: recent fi ndings

  • T Sigsgaard, HJ Hoffman, PS Thorne
  • Curr Opin Allergy Clin Immunol 2008,
  • 2008
1 Excerpt

Similar Papers

Loading similar papers…