A possible role for squalene in the pathogenesis of acne. I. In vitro study of squalene oxidation.

@article{SaintLger1986APR,
  title={A possible role for squalene in the pathogenesis of acne. I. In vitro study of squalene oxidation.},
  author={D. Saint-L{\'e}ger and A Bague and Edmund Cohen and Martine Chivot},
  journal={The British journal of dermatology},
  year={1986},
  volume={114 5},
  pages={535-42}
}
An in vitro study of the oxidation of squalene, and a description of factors acting on this transformation are presented. Thin layer chromatography was used to quantify the products generated by different oxidation processes. The results clearly show that squalene is a highly effective oxygen-scavenging agent. Its oxidation may first induce comedogenesis… CONTINUE READING