A possible role for Ca(2+)-ATPase in human sperm capacitation.

@article{Dasgupta1994APR,
  title={A possible role for Ca(2+)-ATPase in human sperm capacitation.},
  author={Siddhartha Dasgupta and Clytee L Mills and Lynn R. Fraser},
  journal={Journal of reproduction and fertility},
  year={1994},
  volume={102 1},
  pages={107-16}
}
Mammalian spermatozoa require extracellular Ca2+, some of which must be internalized, to undergo capacitation and acrosomal exocytosis. The mechanisms controlling the intracellular Ca2+ concentration are unclear, but current evidence suggests that a Ca(2+)-ATPase may be involved. Using treatments that potentially modulate enzyme activity, we investigated… CONTINUE READING