A possible link between molecular evolution and tissue evolution demonstrated by tissue specific genes.

@article{Miyata1994APL,
  title={A possible link between molecular evolution and tissue evolution demonstrated by tissue specific genes.},
  author={Takashi Miyata and Kei-ichi Kuma and Naoyuki Iwabe and Naruo Nikoh},
  journal={Idengaku zasshi},
  year={1994},
  volume={69 5},
  pages={473-80}
}
In this paper, we reviewed our recent works on a possible link between molecular evolution and tissue evolution. The evolutionary rates of genes that are expressed tissue specifically were shown to differ widely to one another, depending on tissues: Brain specific genes evolve with significantly slower rate than immune specific genes. The tissue dependence of molecular evolutionary rate strongly suggests the presence of functional constraints against molecular changes from tissue level. A… CONTINUE READING

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