A possible link between increased metabolic activity of fat tissue and aortic wall inflammation in subjects with COPD. A retrospective 18F-FDG-PET/CT pilot study.

@article{Vanfleteren2014APL,
  title={A possible link between increased metabolic activity of fat tissue and aortic wall inflammation in subjects with COPD. A retrospective 18F-FDG-PET/CT pilot study.},
  author={Lowie E G W Vanfleteren and Aniek van Meerendonk and Frits M E Franssen and Emiel F. M. Wouters and Felix M. Mottaghy and Marinus P G van Kroonenburgh and Jan Bucerius},
  journal={Respiratory medicine},
  year={2014},
  volume={108 6},
  pages={
          883-90
        }
}
BACKGROUND Fat tissue, and particularly visceral fat, is known to play a role in low grade systemic inflammation in COPD, and is likely to contribute to the excess cardiovascular comorbidity in COPD. Therefore, we aimed to study (18)FDG-PET-assessed inflammation of the aorta and the (visceral) fat, and evaluate its interrelations and differences in subjects with and without COPD. METHODS We retrospectively identified 42 patients (71% male, 48% current smokers, mean age 66.6 ± 8.3 years, mean… CONTINUE READING
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