A possible link between early probiotic intervention and the risk of neuropsychiatric disorders later in childhood: a randomized trial

  title={A possible link between early probiotic intervention and the risk of neuropsychiatric disorders later in childhood: a randomized trial},
  author={Anna P{\"a}rtty and Marko Kalliom{\"a}ki and Pirjo Wacklin and Seppo Salminen and Erika Isolauri},
  journal={Pediatric Research},
Background:Recent experimental evidence suggests that gut microbiota may alter function within the nervous system providing new insight on the mechanism of neuropsychiatric disorders.Methods:Seventy-five infants who were randomized to receive Lactobacillus rhamnosus GG (ATCC 53103) or placebo during the first 6 mo of life were followed-up for 13 y. Gut microbiota was assessed at the age of 3 wk, 3, 6, 12, 18, 24 mo, and 13 y using fluorescein in situ hybridization (FISH) and qPCR, and… 

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