A possible key role of vision in the development of schizophrenia

@article{Csszr2019APK,
  title={A possible key role of vision in the development of schizophrenia},
  author={No{\'e}mi Cs{\'a}sz{\'a}r and G{\'a}bor Kap{\'o}cs and Istv{\'a}n B{\'o}kkon},
  journal={Reviews in the Neurosciences},
  year={2019},
  volume={30},
  pages={359 - 379}
}
Abstract Based on a brief overview of the various aspects of schizophrenia reported by numerous studies, here we hypothesize that schizophrenia may originate (and in part be performed) from visual areas. In other words, it seems that a normal visual system or at least an evanescent visual perception may be an essential prerequisite for the development of schizophrenia as well as of various types of hallucinations. Our study focuses on auditory and visual hallucinations, as they are the most… 
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Antipsychotic agents deteriorate brain and retinal function in schizophrenia patients with combined auditory and visual hallucinations: A pilot study and secondary follow‐up study
TLDR
There is an urgent need for a study that investigates the trajectory of brain and retinal alterations in patients with first‐episode untreated schizophrenia accompanied by combined AHs and VHs (FUSCHAV).
Classic psychedelics: the special role of the visual system
TLDR
It is hypothesized that the brain has an ancient visual-based (preverbal) intrinsic cognitive process that, during the transient inhibition of top-down convergent and abstract thinking (mediated by the prefrontal cortex) by psychedelics, can neutralize emotional fears of unconscious and conscious life experiences from the past.
Abberant inverted U-shaped brain pattern and trait-related retinal impairment in schizophrenia patients with combined auditory and visual hallucinations: a pilot study
TLDR
Findings indicate a reciprocal deterioration in auditory and visual disturbances among FUSCHAV patients, and brain and retinal alterations associated with combined AHs and VHs in schizophrenia patients are unknown.
Psychotic symptoms and sensory impairment: Findings from the 2014 adult psychiatric morbidity survey
Alterations of dynamic functional connectivity between visual and executive-control networks in schizophrenia.
TLDR
It is found that patients with schizophrenia exhibited higher occurrences in the weakly and sparsely connected state than healthy controls, positively correlated with negative symptoms, and that alterations of dynamic functional network connectivity features might be a fundamental neural mechanism in schizophrenia.
A cholinergic medial septum input to medial habenula mediates generalization formation and extinction of visual aversion.
TLDR
Findings reveal that the MS→MHb cholinergic circuit is a critical node in aversion-generalization formation and extinction and potentially provides insight into the pathogenesis of affective disorders.
Modeling the Hallucinating Brain: A Generative Adversarial Framework
TLDR
Focusing on visual hallucination and its underlying causes, this paper identifies an adversarial mechanism between different parts of the brain which are responsible in the process of visual perception and shows how the characterized adversarial interactions in the brain can be modeled by a generative adversarial network.
Recent updates of eye movement abnormalities in patients with schizophrenia: A scoping review
TLDR
This work undertakes a scoping review of research on saccadic dysfunctions and exploratory eye movement deficits among patients with schizophrenia and gathers promising pieces of evidence of eye movement abnormalities in attention‐demanding tasks on the schizophrenia spectrum and their outcomes as potential biological markers.

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