A positive effect of AII inhibitors on peritoneal membrane function in long-term PD patients.

@article{Kolesnyk2009APE,
  title={A positive effect of AII inhibitors on peritoneal membrane function in long-term PD patients.},
  author={Inna Kolesnyk and Marlies Noordzij and Friedo Wilhelm Dekker and Elisabeth Wilhelmina Boeschoten and Raymond Theodorus Krediet},
  journal={Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association},
  year={2009},
  volume={24 1},
  pages={272-7}
}
BACKGROUND Experimental studies showed that inhibition of AII effects attenuates the development of peritoneal membrane fibrosis and neoangiogenesis. The latter leads to an increase of peritoneal solute transport and ultrafiltration failure. The results of a single-centre study showed that use of ACEI/ARB can prevent the increase of small solute transport in long-term PD patients. Our aim was to investigate whether these results would also be present in a larger population and influence patient… CONTINUE READING