A population of myogenic stem cells that survives skeletal muscle aging.

@article{Collins2007APO,
  title={A population of myogenic stem cells that survives skeletal muscle aging.},
  author={Charlotte A. Collins and Peter S Zammit and Ana P{\'e}rez Ruiz and Jennifer Elizabeth Morgan and Terence A. Partridge},
  journal={Stem cells},
  year={2007},
  volume={25 4},
  pages={885-94}
}
Age-related decline in integrity and function of differentiated adult tissues is widely attributed to reduction in number or regenerative potential of resident stem cells. The satellite cell, resident beneath the basal lamina of skeletal muscle myofibers, is the principal myogenic stem cell. Here we have explored the capacity of satellite cells within aged mouse muscle to regenerate skeletal muscle and to self-renew using isolated myofibers in tissue culture and in vivo. Satellite cells… CONTINUE READING
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