A pooled analysis of vitamin D dose requirements for fracture prevention.

  title={A pooled analysis of vitamin D dose requirements for fracture prevention.},
  author={H. Bischoff-Ferrari and W. Willett and E. Orav and P. Lips and P. Meunier and R. Lyons and L. Flicker and J. Wark and R. Jackson and J. Cauley and H. Meyer and M. Pfeifer and K. Sanders and H. Staehelin and R. Theiler and B. Dawson-Hughes},
  journal={The New England journal of medicine},
  volume={367 1},
  • H. Bischoff-Ferrari, W. Willett, +13 authors B. Dawson-Hughes
  • Published 2012
  • Medicine
  • The New England journal of medicine
  • BACKGROUND The results of meta-analyses examining the relationship between vitamin D supplementation and fracture reduction have been inconsistent. METHODS We pooled participant-level data from 11 double-blind, randomized, controlled trials of oral vitamin D supplementation (daily, weekly, or every 4 months), with or without calcium, as compared with placebo or calcium alone in persons 65 years of age or older. Primary end points were the incidence of hip and any nonvertebral fractures… CONTINUE READING
    676 Citations
    Randomized controlled trial of vitamin D supplementation in older people to optimize bone health
    • 8
    • PDF
    Vitamin D and Calcium for the Prevention of Fracture
    • 12
    • PDF
    Vitamin D supplements with or without calcium to prevent fractures.
    • 45
    • Highly Influenced
    • PDF
    Should vitamin D administration for fracture prevention be continued?
    • 6
    Calcium plus vitamin D supplementation and risk of fractures: an updated meta-analysis from the National Osteoporosis Foundation
    • 232
    • PDF


    Calcium plus vitamin D supplementation and the risk of fractures.
    • 1,642
    • PDF
    Can Vitamin D Supplementation Reduce the Risk of Fracture in the Elderly? A Randomized Controlled Trial
    • 222