A polysomnographic placebo-controlled evaluation of the efficacy and safety of eszopiclone relative to placebo and zolpidem in the treatment of primary insomnia.

@article{Erman2008APP,
  title={A polysomnographic placebo-controlled evaluation of the efficacy and safety of eszopiclone relative to placebo and zolpidem in the treatment of primary insomnia.},
  author={Milton K. Erman and Gary K. Zammit and Robert P Rubens and Kendyl Schaefer and Thomas C. Wessel and David A. Amato and Judy Caron and James K Walsh},
  journal={Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine},
  year={2008},
  volume={4 3},
  pages={229-34}
}
STUDY OBJECTIVES To evaluate the polysomnographic efficacy and the safety of a range of doses of eszopiclone relative to placebo in patients with primary insomnia. Zolpidem 10 mg was included as an active control. METHODS This multicenter, randomized, crossover study enrolled patients aged 21-64 years meeting the DSM-IV criteria for primary insomnia (n = 65). Patients received 2 nights treatment each with placebo, eszopiclone 1 mg, 2 mg, 2.5 mg, or 3 mg, and zolpidem 10 mg after randomization… CONTINUE READING

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, quality of life , and work limitations

  • A Rechtschaffen, A Kales
  • 2007

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