A polysaccharide from Trametes robiniophila inhibits human osteosarcoma xenograft tumor growth in vivo.

@article{Zhao2015APF,
  title={A polysaccharide from Trametes robiniophila inhibits human osteosarcoma xenograft tumor growth in vivo.},
  author={X. Zhao and S. Ma and N. Liu and Jiakun Liu and W. Wang},
  journal={Carbohydrate polymers},
  year={2015},
  volume={124},
  pages={
          157-63
        }
}
  • X. Zhao, S. Ma, +2 authors W. Wang
  • Published 2015
  • Chemistry, Medicine
  • Carbohydrate polymers
  • In the present study, we isolated and purified one polysaccharide (TRP) from Trametes robiniophila, which had a backbone of 1,3,6- and 1,4-linked glucpyranosyl moieties, with 1-linked arabinofuranosyl and galactopyranosyl terminal at the O-3 position of 1,3,6-linked glucpyranosyl residues. TRP was further evaluated for its antitumor activity against xenografted U-2 OS osteosarcoma in BALB/c nude mice together with the possible mechanism of action. We found that oral administration of TRP… CONTINUE READING
    11 Citations
    Effect of Huai Qi Huang on Epithelial-Mesenchymal Transition of Renal Tubular Epithelial Cells through miR-200a
    • 8
    • PDF

    References

    SHOWING 1-10 OF 53 REFERENCES
    Antitumor activity of a polysaccharide fraction from Laminaria japonica on U14 cervical carcinoma-bearing mice
    • 16
    A Huaier polysaccharide inhibits hepatocellular carcinoma growth and metastasis
    • 32
    A polysaccharide from the fungi of Huaier exhibits anti-tumor potential and immunomodulatory effects.
    • 67
    • PDF
    Anti-angiogenic and antitumor activities of Huaier aqueous extract
    • 59
    • PDF
    Inhibitory effect of extract of fungi of Huaier on hepatocellular carcinoma cells
    • Jianzhuang Ren, Chuansheng Zheng, +5 authors Hui Zhao
    • Biology, Medicine
    • Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban
    • 2009
    • 20
    Huaier polysaccharides suppresses hepatocarcinoma MHCC97-H cell metastasis via inactivation of EMT and AEG-1 pathway.
    • 48
    Oxymatrine induces mitochondria dependent apoptosis in human osteosarcoma MNNG/HOS cells through inhibition of PI3K/Akt pathway
    • 49