A polypurine sequence that acts as a 5' mRNA stabilizer in Bacillus subtilis.

@article{Hue1995APS,
  title={A polypurine sequence that acts as a 5' mRNA stabilizer in Bacillus subtilis.},
  author={K K Hue and Steven D. Cohen and David H. Bechhofer},
  journal={Journal of bacteriology},
  year={1995},
  volume={177 12},
  pages={3465-71}
}
A segment of early RNA from Bacillus subtilis bacteriophage SP82 was shown to function as a 5' stabilizer in B. subtilis. Several heterologous RNA sequences were stabilized by the presence of the SP82 sequence at the 5' end, and expression of downstream coding sequences was increased severalfold. The SP82 RNA segment encodes a B. subtilis RNase III cleavage site, but cleavage by B. subtilis RNase III was not required for stabilization. The sequence that specifies 5' stabilizer function was… CONTINUE READING