A polymorphism near IL28B is associated with spontaneous clearance of acute hepatitis C virus and jaundice.

@article{Tillmann2010APN,
  title={A polymorphism near IL28B is associated with spontaneous clearance of acute hepatitis C virus and jaundice.},
  author={Hans L Tillmann and Alexander J Thompson and Keyur A. Patel and Manfred Wiese and Hannelore Tenckhoff and Hans Dieter Nischalke and Yuliya V Lokhnygina and Ulrike Kullig and Uwe Goebel and Emanuela Capka and J Wiegand and Ingolf Schiefke and Wolfgang G{\"u}thoff and Kurt Gruengreiff and Ingrid K{\"o}nig and Ulrich Spengler and Jeanette McCarthy and Kevin V. Shianna and David K. Goldstein and John McHutchison and Joerg Timm and Jacob Nattermann},
  journal={Gastroenterology},
  year={2010},
  volume={139 5},
  pages={1586-92, 1592.e1}
}
BACKGROUND & AIMS A single nucleotide polymorphism (SNP) upstream of the IL28B gene has been associated with response of patients with chronic hepatitis C to therapy with pegylated interferon and ribavirin and also with spontaneous clearance of acute hepatitis C in a heterogeneous population. We analyzed the association between IL28B and the clinical presentation of acute hepatitis C virus (HCV) infection in a homogeneous population. METHODS We analyzed the SNP rs12979860 in 190 women from… CONTINUE READING