A polymorphism in the serotonin receptor 3A (HTR3A) gene and its association with harm avoidance in women.

BACKGROUND The brain neurotransmitter serotonin is known to affect various aspects of human behavior, including personality traits. Serotonin receptor type 3 is a ligand-gated channel encoded by 2 different subunit genes, HTR3A and HTR3B. A polymorphism (C178T) in the 5' region of the HTR3A gene has recently been identified and suggested to be of functional… CONTINUE READING