A polymorphism in the beta1 adrenergic receptor is associated with resting heart rate.

@article{Ranade2002API,
  title={A polymorphism in the beta1 adrenergic receptor is associated with resting heart rate.},
  author={K. Ranade and E. Jorgenson and W. Sheu and D. Pei and C. Hsiung and F. Chiang and Yii-Der I. Chen and R. Pratt and R. Olshen and D. Curb and D. Cox and D. Botstein and N. Risch},
  journal={American journal of human genetics},
  year={2002},
  volume={70 4},
  pages={
          935-42
        }
}
Resting heart rate is significantly associated with cardiovascular morbidity and mortality. However, the extent to which resting heart rate is genetically determined is poorly understood, and no genes have been found that contribute to variation in resting heart rate. Because signaling through the beta1 adrenergic receptor is a key determinant of cardiac function, we tested whether polymorphisms in this receptor are associated with resting heart rate. A cohort of >1,000 individuals of Chinese… Expand
Adrenergic Receptor Polymorphisms Associated with Resting Heart Rate: The HyperGEN Study
Association of beta-adrenoceptor single nucleotide polymorphisms with resting heart rate
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