A polymorphism in npr-1 is a behavioral determinant of pathogen susceptibility in C. elegans.


The nematode Caenorhabditis elegans responds to pathogenic bacteria with conserved innate immune responses and pathogen avoidance behaviors. We investigated natural variation in C. elegans resistance to pathogen infection. With the use of quantitative genetic analysis, we determined that the pathogen susceptibility difference between the laboratory wild… (More)
DOI: 10.1126/science.1166527


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