A polymerase chain reaction-based protocol for the detection of transmission of pig endogenous retroviruses in pig to human xenotransplantation.

Abstract

BACKGROUND Xenotransplantation of pig organs and tissues to humans bears the risk of infection of immunosuppressed recipients by porcine endogenous retrovirus (PERV) released from the transplanted tissue. However, when diagnosing potential PERV transmission, it is essential to exclude microchimerism, i.e., persisting pig cells in analyzed bioptic material… (More)

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@article{Blusch2000APC, title={A polymerase chain reaction-based protocol for the detection of transmission of pig endogenous retroviruses in pig to human xenotransplantation.}, author={J{\"u}rgen H. Blusch and C. Roos and H. M. Nitschko}, journal={Transplantation}, year={2000}, volume={69 10}, pages={2167-72} }