A polymer-based neural microimplant for optogenetic applications: design and first in vivo study.

@article{Rubehn2013APN,
  title={A polymer-based neural microimplant for optogenetic applications: design and first in vivo study.},
  author={Birthe Rubehn and Steffen B. E. Wolff and Philip Tovote and Andreas L{\"u}thi and Thomas Stieglitz},
  journal={Lab on a chip},
  year={2013},
  volume={13 4},
  pages={579-88}
}
In optogenetics, neurons are genetically modified to become sensitive to light and thus, they can be stimulated or inhibited by light of certain wavelengths. In this work, we describe the fabrication of a polymer-based shaft electrode as a tool for optogenetics. This device can conduct light as well as fluids to a target brain region and record electrical neural signals from the same part of the tissue simultaneously. It is intended to facilitate optogenetic in vivo experiments with those novel… CONTINUE READING
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