A polyketide synthase gene, ACRTS2, is responsible for biosynthesis of host-selective ACR-toxin in the rough lemon pathotype of Alternaria alternata.

@article{Izumi2012APS,
  title={A polyketide synthase gene, ACRTS2, is responsible for biosynthesis of host-selective ACR-toxin in the rough lemon pathotype of Alternaria alternata.},
  author={Yuriko Izumi and Kouhei Ohtani and Yoko Miyamoto and Akira Masunaka and Takeshi Fukumoto and Kenji Gomi and Yasuomi Tada and Kazuya Ichimura and Tobin L. Peever and Kazuya Akimitsu},
  journal={Molecular plant-microbe interactions : MPMI},
  year={2012},
  volume={25 11},
  pages={1419-29}
}
The rough lemon pathotype of Alternaria alternata produces host-selective ACR-toxin and causes Alternaria leaf spot disease of rough lemon (Citrus jambhiri). The structure of ACR-toxin I (MW = 496) consists of a polyketide with an α-dihydropyrone ring in a 19-carbon polyalcohol. Genes responsible for toxin production were localized to a 1.5-Mb chromosome in the genome of the rough lemon pathotype. Sequence analysis of this chromosome revealed an 8,338-bp open reading frame, ACRTS2, that was… CONTINUE READING
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