A polycomb group protein, PHF1, is involved in the response to DNA double-strand breaks in human cell

@inproceedings{Hong2008APG,
  title={A polycomb group protein, PHF1, is involved in the response to DNA double-strand breaks in human cell},
  author={Zehui Hong and Jie Jiang and Li Ying Lan and Satoshi Nakajima and Shin-ichiro Kanno and Haruhiko Koseki and Akira Yasui},
  booktitle={Nucleic acids research},
  year={2008}
}
DNA double-strand breaks (DSBs) represent the most toxic DNA damage arisen from endogenous and exogenous genotoxic stresses and are known to be repaired by either homologous recombination or nonhomologous end-joining processes. Although many proteins have been identified to participate in either of the processes, the whole processes still remain elusive. Polycomb group (PcG) proteins are epigenetic chromatin modifiers involved in gene silencing, cancer development and the maintenance of… CONTINUE READING
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