A poly(ε-caprolactone) device for sustained release of an anti-glaucoma drug.

@article{Natu2011APD,
  title={A poly(ε-caprolactone) device for sustained release of an anti-glaucoma drug.},
  author={Mădălina V. Natu and Manuel N Gaspar and Carlos Alberto Fontes Ribeiro and Il{\'i}dio J Correia and Daniela Lucas da Silva and Herm{\'i}nio Jos{\'e} Cipriano de Sousa and M. H. Gil},
  journal={Biomedical materials},
  year={2011},
  volume={6 2},
  pages={025003}
}
Implantable dorzolamide-loaded discs were prepared by blending poly(ε-caprolactone), PCL, with poly(ethylene oxide)-b-poly(propylene oxide)-b-poly(ethylene oxide), Lu. By blending, crystallinity, water uptake and mass loss were modified relative to the pure polymers. Burst was diminished by coating the discs with a PCL shell. All samples presented burst… CONTINUE READING