A platelet-endothelium interaction mediated by lectin-like oxidized low-density lipoprotein receptor-1.

@article{Kakutani2000API,
  title={A platelet-endothelium interaction mediated by lectin-like oxidized low-density lipoprotein receptor-1.},
  author={Makoto Kakutani and Tomoh Masaki and Tatsuya Sawamura},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={2000},
  volume={97 1},
  pages={360-4}
}
One crucial role of endothelium is to keep the innermost surface of a blood vessel antithrombotic. However, the endothelium also expresses prothrombotic molecules in response to various stimuli. The balance between the antithrombotic and prothrombotic nature of the endothelium is lost under certain conditions. During atherosclerosis, the attachment of platelets to the vessel surface has been suggested to promote the proliferation of smooth muscle cells and intimal thickening as well as to… CONTINUE READING

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