A plasma inhibitor of platelet aggregation in patients with Lassa fever.

@article{Cummins1989API,
  title={A plasma inhibitor of platelet aggregation in patients with Lassa fever.},
  author={David Cummins and Susan P. Fisher-Hoch and Kieran M J Walshe and Ian Mackie and Joseph B Mccormick and Derrick C Bennett and Guido Perez and Bryn Farrar and Samuel J. Machin},
  journal={British journal of haematology},
  year={1989},
  volume={72 4},
  pages={543-8}
}
Previous studies have shown that haemorrhage in Lassa fever is associated with abnormal in vitro platelet aggregation and a high mortality. In Sierra Leone we studied platelet aggregation in healthy local subjects, patients with laboratory-confirmed Lassa fever and febrile patients in whom Lassa virus infection was excluded. There were no significant differences in the mean platelet counts of these groups. Patients with fulminant Lassa virus infection showed a gross depression of in-vitro… CONTINUE READING