A placental-derived tissue matrix as a bowel wall substitute in rats: preliminary study.


BACKGROUND Occasionally, conventional closure of an intestinal wall defect (fistula) is not possible. The development of a biologic material that can be used in this setting would solve a significant clinical problem. We hypothesized that a collagen patch (connective tissue matrix [CTM]) designed to allow tissue regeneration was such a material. METHODS… (More)


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